Ground Truths Seth Berkley & Eric Topol - Discuss Fair Doses Book
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Nov 5, 2025 
Seth Berkley, a prominent physician-epidemiologist and global vaccine leader, shares insights from his book, Fair Doses. He recounts the formation of COVAX and its early challenges, including regulatory delays and vaccine nationalism. Discussion highlights include the unprecedented speed of mRNA vaccine development, the impact of vaccine hesitancy, and the importance of continuous vaccine research. Seth emphasizes the need for sustained investment in global health to ensure equitable vaccine access and prepare for future pandemics.
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Davos Napkin Laid Groundwork For COVAX
- Seth Berkley and partners sketched COVAX at Davos in January 2020 before the pandemic was widely acknowledged.
- They then mobilized partners and funding to launch the largest and fastest global vaccine rollout in history.
Regulatory Delays Slowed Early Rollout
- COVAX achieved rapid global reach despite obstacles, reaching 100 countries within weeks of initial deliveries.
- Early regulatory differences delayed some rollouts, highlighting the need for faster harmonized approvals.
Speed Came From Decades Of Prep
- Vaccines were developed and deployed in unprecedented time because decades of prior research and risk-taking investments enabled rapid action.
- mRNA was uniquely fast and should remain a core tool for future pandemic response.
