
Super Brain S6E11 THe Science of Serendipity
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Jan 22, 2026 They explore famous happy accidents like penicillin and the microwave. The conversation traces the word’s Persian-fairy-tale origin and why curiosity fuels discovery. Neuroscience of insight is highlighted, focusing on brain network coupling. Research on why ‘lucky’ people notice more is discussed. Practical tools for increasing chance encounters and creative luck are shared.
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Fleming's Contaminated Petri Dish
- Alexander Fleming noticed a contaminated Petri dish that showed a halo where bacteria wouldn't grow and pursued it.
- That curiosity and follow-up investigation led to the discovery of penicillin.
Chocolate In The Lab Sparked The Microwave
- Percy Spencer discovered that a chocolate bar in his pocket melted near a magnetron and then tested popcorn and eggs.
- His curiosity about that unexpected melting led to developing microwave cooking.
Failed Glue Became Post-It Notes
- Spencer Silver invented a weak, removable adhesive and kept talking about it despite it being a 'failed' product.
- Art Fry later used that adhesive to create the Post-it note by matching the material to a real need.




