Nature Podcast

Ancient DNA reveals farming led to more human diseases

21 snips
Jul 9, 2025
Cathy Le Fay, a NOAA Fisheries expert, explores how ancient DNA reveals the impact of agriculture on human health. She discusses the emergence of infectious diseases over the last 35,000 years, showing that close contact with domesticated animals heightened disease risks. Their research also highlights how analyzing whale feces sheds light on toxic algae in warming Arctic waters, demonstrating the complex interactions within marine ecosystems. The findings underscore the broader implications of climate change on both wildlife and human health.
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INSIGHT

Agriculture Increased Disease Spread

  • The transition to farming 6,500 years ago led to a marked increase in infectious diseases from animals.
  • Pathogens became more common as humans domesticated livestock and lived in larger settlements.
INSIGHT

Limitations of Ancient DNA

  • Ancient DNA methods cannot detect RNA viruses or diseases with low bloodstream presence, like tuberculosis.
  • This limitation means some high-impact diseases remain invisible to current ancient DNA studies.
INSIGHT

Future Directions for Pathogenomics

  • Expanding studies to more individuals and regions will clarify ancient pathogen dynamics.
  • Including animal remains and social factors may reveal causes of disease outbreaks in past populations.
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