Run the List Septic Shock
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Jul 21, 2025 Dr. Vikramjit Mukherjee, a critical care physician specializing in septic shock management, joins Dr. Emily Gutowski for an eye-opening discussion. They break down the differences between SIRS, sepsis, and septic shock, highlighting essential identification techniques. The conversation also dives into recognizing infection sources and red flags, along with the importance of timely fluid resuscitation for vulnerable patients. Lastly, they detail the critical use of vasopressors, emphasizing the need for swift action in improving patient survival.
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Understanding Septic Shock
- Septic shock is the most severe form of infection-induced systemic inflammation with persistent hypotension despite fluids.
- Differentiating SIRS, sepsis, severe sepsis, and septic shock helps triage and risk-stratify patients effectively.
Check Lungs, Lines, Bowel, Bladder
- Always check the two L's (lungs, lines) and two B's (bowel, bladder) for common septic shock sources.
- These four sources account for about 80% of cases, making them a good initial focus for infection search.
Early Fluids and Antibiotics Save Lives
- Initiate early aggressive fluid resuscitation with 30 cc/kg crystalloids within the first 3 hours.
- Start early, appropriate antibiotics and check lactate urgently to reduce mortality dramatically.