Inside Curology: From Prescription-Only Telehealth to National OTC Retail Brand

In this episode of Ecommerce On Tap, hosts Aaron Alpeter and Nathan Resnick take you through the incredible journey of Curology—the team that managed to build a $200 million brand not once, but twice. 🎉

We dive deep into:

• The founding story of Curology and its breakthrough in prescription teledermatology

• The complex regulatory and compliance hurdles of launching in the healthcare industry

• How Curology scaled from a niche telemedicine offering to a DTC powerhouse, and eventually, to major retail shelves like Target, CVS, Walmart, and Amazon

• The company’s remarkable post-pandemic pivot: how they navigated the decline in telehealth demand and reinvented themselves with OTC (over-the-counter) skincare products

• Behind-the-scenes insights into their supply chain, fundraising rounds, growth challenges, operational pivots, and leadership transitions

• Lessons for founders on spotting exit windows, adapting to market shifts, and whether personalization is a competitive moat—or a margin trap

Plus: Hot takes on celebrity economy trends (Sydney Sweeney’s brand impact!), presidential executive orders shaking up e-commerce, and why Curology’s story is a rare case study in business reinvention and resilience.