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Nature Podcast

Bone marrow in the skull plays a surprisingly important role in ageing

Nov 13, 2024
Bong Ng Kho, an author focused on skull bone marrow's role in aging, discusses how this area becomes vital for blood-cell production as we age, offering potential insights into neuroinflammation. Guy Leckenby, a researcher studying lead-205 isotopes, illuminates new methods for dating the Solar System, showcasing how stellar conditions influence their decay. Together, they highlight the surprising resilience of skull marrow and innovative cosmic dating techniques, leaving listeners intrigued by aging and the cosmos.
35:10

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Quick takeaways

  • Skull bone marrow expands with age, helping maintain blood-cell production and potentially countering neuroinflammation, unlike other bone marrows which decline.
  • User behavior significantly influences the spread of misinformation, suggesting that users actively seeking unreliable information are a key factor in the issue.

Deep dives

The Role of Skull Bone Marrow in Aging

Research shows that skull bone marrow may play a significant role in maintaining health as people age. Unlike other bone marrows, which experience deterioration in function due to various factors such as loss of blood vessels and inflammation, skull bone marrow appears to expand and retain its hematopoietic function throughout the lifespan. This finding suggests that the skull's bone marrow may compensate for declining functions in other bone compartments as individuals age. The unique structure of skull bone marrow, with its connection to the brain's protective membranes, further indicates its potential role in countering neuroinflammation that increases with age.

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