DarkHorse Podcast Wisdom of the Ancients: Dr. Robert Clancy on DarkHorse
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May 30, 2025 In this engaging discussion, Dr. Robert Clancy, Emeritus Professor specializing in mucosal immunology, delves into the complexities of the immune system and its role in respiratory health. He challenges misconceptions about vaccines and emphasizes the significance of the microbiome. The conversation spans the effects of inflammation, innovative health products, and the critical importance of understanding our immune dynamics. Dr. Clancy advocates for a paradigm shift in health practices, urging a more holistic and truthful approach to immunity and wellness.
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Mucosal vs Systemic Immunity
- The mucosal immune system protects wet surfaces like lungs, mouth, nose, and gut, distinct from systemic immunity.
- Injected vaccines stimulate systemic immunity but do not effectively protect the airway mucosa where respiratory infections occur.
Lung-Gut Immune Education Loop
- Lungs export pathogens via mucus to Peyer's patches in the gut to educate immune cells.
- These educated T and B cells circulate back to the lung mucosa to provide targeted immunity.
T Cell-Cytokine Immune Activation
- T cells recruited to lung mucosa release cytokines that stimulate white blood cells to engulf pathogens.
- This adaptive immunity enhances innate immune cell activity through a self-stimulating autocrine loop.