Bankless

DeSci: How Blockchains are Powering Science 3.0 | Zuzalu #7

Aug 16, 2023

Boris Dyakov, a PhD candidate at the University of Toronto, Mikey Fischer, a recent Stanford PhD in computer science, and Alok Tayi, founder of Vibe Bio, dive into the transformative realm of Decentralized Science (DeSci). They discuss how blockchain can revolutionize traditional scientific practices, making research more transparent and collaborative. Alok shares how Vibe Bio is addressing underfunded diseases, while the group explores the role of DAOs in funding clinical trials, highlighting groundbreaking opportunities for community-driven scientific innovation.

01:19:47

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Episode guests

Alok Tayi

Mikey Fischer

Boris Dyakov

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Episode notes

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Quick takeaways

DeSci aims to revolutionize the scientific system by leveraging blockchain technology to address flaws such as friction, corruption, and outdated practices.

Blockchain and crypto can provide solutions for improved capital coordination, transparent funding mechanisms, data provenance, and incentivization of research contributions in the field of decentralized science (D-Sci).

Vibe Bio aims to enhance the community-driven drug development model through the use of DAOs, enabling patient communities to engage in governance and allocation of capital for neglected diseases in the long tail of diseases.

Deep dives

The Problem of Long Tail Diseases

The podcast episode discusses the issue of diseases that are not prioritized or addressed in the current medical system, often referred to as the long tail of diseases. These are diseases with a measurable amount of unmet need, but are deprioritized due to the current incentive structure within the pharmaceutical industry. The focus tends to be on larger diseases with higher potential for profit, leaving many diseases without dedicated therapeutic options.

Intro

4min

Navigating the DeFi Landscape: Tools and Technologies for Success

3min

Decentralizing Science: The DeSci Movement

7min

Revolutionizing Science with Decentralization

16min

Decentralized Science: Bridging Art and Finance

12min

From Researcher to Biotech Entrepreneur

12min

Unveiling the Hidden Prevalence of Diseases Through Treatment Innovations

2min

Transformative Community-Driven Drug Development

2min

Revolutionizing Rare Disease Funding

18min

10.

Exploring the Integration of Crypto into Mainstream Society

2min

11.

Empowering Communities Through Capital Coordination

2min

In this episode, we delve into the world of DeSci, or Decentralized Science, which serves as a bridge between technologies like Synthetic Biology, Longevity, and Ethereum. DeSci aims to revolutionize the current scientific system, highlighting its flaws such as friction, corruption, and outdated practices. By utilizing blockchain technology, DeSci seeks to improve scientific institutions and processes.

The conversation with pioneers Boris Dyakov and Mikey Fischer sheds light on the vast potential of DeSci and its ability to transform scientific progress. It goes beyond mere improvement, presenting a paradigm shift in the way science is conducted. The second conversation with Alok Tayi of VibeBio illustrates a fascinating use case for using DeSci to solve diseases that are underserved in TradSci.

DeSci envisions open and modular scientific data, akin to the accessibility of financial tools in the blockchain world. Additionally, the emergence of DAOs in DeSci brings opportunities for capital allocation and funding clinical trials. Join us on this exploration of the frontier of Scientific Progress, where traditional and decentralized science collide.

------ Timestamps

0:00 Intro 1:30 Scientific Progress

5:30 BORIS & MIKEY 8:50 Overcoming TradSci 13:00 Open Science 16:25 VitaDAO 19:00 What is DeSci? 23:23 Bullish on Science 28:30 Onboarding Scientists 34:00 The New Infrastructure 35:00 AI and Science

43:00 ALOK TAYI 44:10 Vibe Bio 47:00 The Long Tail of Disease 52:00 Inflection Points 54:00 Solving Disease 59:45 The Power of DAOs 1:07:45 Governance and Structure 1:11:30 The Crypto Value Add 1:14:00 Regulation 1:19:00 A New Primitive

------ Resources

Boris Dyakov https://twitter.com/BJ_Dyakov?s=20

Mikey Fischer https://twitter.com/0xMikeyF?s=20

Alok Tayi https://twitter.com/aloktayi?s=20

DeSci Ethereum Foundation https://ethereum.org/en/desci/

Gitcoin DeSci Fund https://bounties.gitcoin.co/grants/5105/the-decentralized-science-community-fund

Vibe Bio https://www.vibebio.com/

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Bankless

DeSci: How Blockchains are Powering Science 3.0 | Zuzalu #7

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

Deep dives

The Problem of Long Tail Diseases

The Complex Process of Drug Development

Capital Coordination and Incentive Alignment

The Role of Blockchain and Crypto in D-Sci

Harnessing the Power of Patient Communities

Vibe Bio's Approach and the Potential of DAOs

Remember Everything You Learn from Podcasts