DeSci: How Blockchains are Powering Science 3.0 | Zuzalu #7

Aug 16, 2023

Guest

Alok Tayi

Guest

Mikey Fischer

Guest

Boris Dyakov

Boris Dyakov, a PhD candidate at the University of Toronto, Mikey Fischer, a recent Stanford PhD in computer science, and Alok Tayi, founder of Vibe Bio, dive into the transformative realm of Decentralized Science (DeSci). They discuss how blockchain can revolutionize traditional scientific practices, making research more transparent and collaborative. Alok shares how Vibe Bio is addressing underfunded diseases, while the group explores the role of DAOs in funding clinical trials, highlighting groundbreaking opportunities for community-driven scientific innovation.

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INSIGHT

DeSci's Speed

DeSci aims to accelerate scientific progress, unlike TradSci's slow publishing process.
TradSci can take 2-3 years to publish, lacking the rapid cycles of platforms like GitHub.

INSIGHT

Permissionless Science

Traditional science operates as a permissioned system, requiring grants and approvals.
DeSci, however, is permissionless, allowing anyone with the right data to contribute.

INSIGHT

DeSci's Incentives

DeSci offers incentivization mechanisms, tracking research and rewarding contributions.
Unlike open science, DeSci allows researchers to retain ownership of their data and benefit from its value.

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In this episode, we delve into the world of DeSci, or Decentralized Science, which serves as a bridge between technologies like Synthetic Biology, Longevity, and Ethereum. DeSci aims to revolutionize the current scientific system, highlighting its flaws such as friction, corruption, and outdated practices. By utilizing blockchain technology, DeSci seeks to improve scientific institutions and processes.

The conversation with pioneers Boris Dyakov and Mikey Fischer sheds light on the vast potential of DeSci and its ability to transform scientific progress. It goes beyond mere improvement, presenting a paradigm shift in the way science is conducted. The second conversation with Alok Tayi of VibeBio illustrates a fascinating use case for using DeSci to solve diseases that are underserved in TradSci.

DeSci envisions open and modular scientific data, akin to the accessibility of financial tools in the blockchain world. Additionally, the emergence of DAOs in DeSci brings opportunities for capital allocation and funding clinical trials. Join us on this exploration of the frontier of Scientific Progress, where traditional and decentralized science collide.

------ Timestamps

0:00 Intro 1:30 Scientific Progress

5:30 BORIS & MIKEY 8:50 Overcoming TradSci 13:00 Open Science 16:25 VitaDAO 19:00 What is DeSci? 23:23 Bullish on Science 28:30 Onboarding Scientists 34:00 The New Infrastructure 35:00 AI and Science

43:00 ALOK TAYI 44:10 Vibe Bio 47:00 The Long Tail of Disease 52:00 Inflection Points 54:00 Solving Disease 59:45 The Power of DAOs 1:07:45 Governance and Structure 1:11:30 The Crypto Value Add 1:14:00 Regulation 1:19:00 A New Primitive

------ Resources

Boris Dyakov https://twitter.com/BJ_Dyakov?s=20

Mikey Fischer https://twitter.com/0xMikeyF?s=20

Alok Tayi https://twitter.com/aloktayi?s=20

DeSci Ethereum Foundation https://ethereum.org/en/desci/

Gitcoin DeSci Fund https://bounties.gitcoin.co/grants/5105/the-decentralized-science-community-fund

Vibe Bio https://www.vibebio.com/

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