Health Controversies: Vaccine Politics, GLP-1 Drug Safety, and Psychedelic Research Challenges

Broadcast from KSQD on 9-04-2025:

• Dr. Dawn opens by criticizing new FDA restrictions on simultaneous COVID and flu vaccinations, calling out vaccine regulator Vinay Prasad for creating artificial shortages. She explains that while no formal studies test multiple vaccines together, decades of safe practice demonstrate effectiveness. The FDA's requirement for separate testing ignores practical evidence and threatens vaccine supply chains during critical flu season.
• She discusses Oregon research suggesting adults may not need tetanus boosters every 10 years, but warns this misses the pertussis component. Dr. Dawn explains that acellular pertussis vaccines only provide 4-year immunity, making adult boosters essential to prevent whooping cough transmission to vulnerable infants. The focus should remain on pertussis prevention rather than tetanus economics.
• California, Oregon, and Washington announced a West Coast Health Alliance to maintain scientific integrity in public health policy amid federal changes. Dr. Dawn supports this states' rights approach to vaccination recommendations based on trusted medical organizations, expressing concern about potential vaccine shortages if manufacturers reduce production due to uncertain federal demand.
• An emailer shares an AI-generated analysis comparing tuberculosis and Lyme disease. Dr. Dawn critiques the AI's inaccuracies, noting that while tuberculosis may be present in 25% of people globally s the AI reports (she did not fact check this), the distribution is very uneven and cases in the US are low which we know since accurate latent TB testing is readily available in the US. She warns against AI's tendency to incorporate conspiracy theories due to a bias which favors frequency vs accuracy and emphasizes the importance of fact-checking AI-generated medical content.
• Dr. Dawn addresses FDA concerns about unregulated GLP-1 drugs, warning about counterfeit semaglutide and tirzepatide from questionable sources. She discusses dosing errors, non-FDA-approved compounds appearing in gray markets, and the rare but serious cancer risk for people with multiple endocrine neoplasia syndromes - affecting 1 in 30,000 people who could develop hormone-producing cancers.
• A caller asks about genetic testing for GLP-1 cancer risk. Dr. Dawn explains that complete genome testing costs around $1,000 and requires professional interpretation. She discusses the economic challenges of testing 30,000 people to prevent one cancer case, while acknowledging that obesity's health risks generally outweigh the small cancer risk for most patients.
• She examines FDA challenges in approving MDMA for PTSD treatment, explaining the "Catch-22" of blinding studies when drugs cause obvious consciousness changes. Dr. Dawn describes how psychedelic research faces unique obstacles requiring 8-10 hour supervised sessions with therapists, making traditional double-blind studies nearly impossible to conduct properly.
• An emailer asks about B vitamin effects on brain and heart health. Dr. Dawn warns about high-dose biotin interfering with thyroid tests and troponin levels used to diagnose heart attacks. She explains how B12 deficiency affects 40% of people over 80, recommending methylmalonic acid testing for accurate assessment rather than standard blood levels.
• She discusses research showing coastal living extends life expectancy by over a year compared to inland areas, attributed to cleaner air and better recreational opportunities. However, living near inland waterways may slightly decrease lifespan due to flood risks and environmental factors, suggesting ocean proximity specifically provides health benefits.