TBPN Meta Oakleys, Golden Retriever Maxing, Suits in Airports | John Jumper, Christian Garrett, Aaron Frank, Joseph Cass
22 snips
Jun 16, 2025 
Join John Jumper, a computational biologist at DeepMind, as he reveals how AlphaFold has revolutionized protein structure prediction, making complex research a breeze. Christian Garrett, from 137 Ventures, discusses the precarious position of billion-dollar software companies and the need for competitive strategies. Aaron Frank shares insights on the fintech evolution and AI's game-changing role in financial services, while Joseph Cass offers a peek into engaging with top investors in the financial world, shedding light on market dynamics and investment challenges.
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AlphaFold Revolutionizes Protein Folding
- Protein folding was a 50-year scientific challenge, revolutionized by AlphaFold using AI and data-driven supervised learning.
- The breakthrough reduced process time from a year and $100,000 to minutes, vastly accelerating biology and drug development.
ML Innovations Key to AlphaFold Success
- Early attempts at AlphaFold used reinforcement learning; success came from treating protein folding as a machine learning research problem.
- Tailoring transformer-inspired architectures led to 100-fold better data efficiency and remarkable accuracy improvements.
AlphaFold's Market Impact Nuanced
- AlphaFold's impact on public markets was muted as drug development costs exceed protein folding costs by orders of magnitude.
- The real benefit lies in guiding more effective experiments and protein design, improving success rates and biotech progress.
