Everyday Oral Surgery

Hematology Series: physiology, diagnostic tools, common coagulation pathology (with Drs. Andrew Jenzer and Maxwell Lloyd)

Jan 13, 2025
Join Dr. Andrew Jenzer, an expert running a mock boards course for residents, and Dr. Maxwell Lloyd, a Boston-based hematologic oncologist specializing in breast cancer, as they explore blood and coagulation. They delve into the intricacies of hemostasis, the significance of lab interpretations, and common bleeding disorders like Von Willebrand's disease. Highlights include diagnostic tools for surgical safety, factors impacting coagulation tests, and the implications of key trials on treatment practices. It's a fascinating discussion that brings clarity to complex blood-related issues!
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INSIGHT

Primary vs Secondary Hemostasis

  • Primary hemostasis forms an initial platelet plug through vasoconstriction and platelet aggregation.
  • Secondary hemostasis activates the coagulation cascade creating a stable clot with intrinsic and extrinsic pathways.
ADVICE

Know Coagulation Cascade Cold

  • Master the coagulation cascade thoroughly for clinical and perioperative decision-making.
  • Understanding factor pathways clarifies medication effects and risk stratification for surgery.
INSIGHT

Liver's Role in Coagulation

  • All coagulation factors, except factor VIII and von Willebrand factor, are synthesized in the liver.
  • Advanced liver disease disrupts coagulation, causing severe bleeding and clotting abnormalities.
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