

Superaging with Eric Topol
May 27, 2025
In this engaging discussion, Eric Topol, founder of the Scripps Research Translational Institute and a leading cardiologist and author, shares insights from his book on 'Superagers.' He explores groundbreaking ideas on preventing diseases rather than just curing them, emphasizing personalized data and AI's role in forecasting health risks. They delve into innovative GLP-1 drugs, the biology of aging, and the importance of lifestyle changes for enhancing healthspan. Topol calls for a shift to a preventive healthcare model, promising better outcomes for all.
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Prevention Over Reversal
- Preventing age-related diseases is currently more feasible than reversing aging itself.
- Extending healthspan by seven years free of major diseases is a realistic goal today.
Inspired by a Super Agers' Patient
- Eric Topol's study of people over 87 without age-related diseases revealed minimal genetic influence.
- A 98-year-old patient who never got sick inspired deeper exploration of longevity.
Two Paths in Aging Science
- Two approaches to aging: reversing aging versus preventing age-related diseases.
- Preventing cardiovascular, cancer, and neurodegenerative diseases is the more immediate achievable path.