Clinical Characteristics and Long-Term Outcomes of Late-Onset MS
Apr 26, 2024
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Dr. Abbatemarco and Dr. Iacobaeus discuss the impact of late-onset MS, including poor prognosis risk factors, diagnostic delays, higher disability levels, less frequent treatment, and faster disease progression in patients with late-onset MS.
Late-onset MS patients have poorer prognosis due to risk factors, with higher disability levels at onset.
Late-onset MS patients receive fewer disease-modifying therapies and show faster disability progression despite treatments.
Deep dives
Late-onset MS Patients Face Poor Prognosis
Late-onset MS patients, whose symptoms appear after the age of 50, were found to be associated with several risk factors linked to a poorer prognosis. A significant portion of these patients exhibited primary progressive MS. The diagnosis for late-onset MS patients experienced delays compared to those with adult-onset MS. Additionally, late-onset MS patients showed higher disability levels at onset and had a faster progression of disabilities post-onset, despite potential treatments.
Clinical Characteristics and Treatment Disparities in Late-onset MS
In the study, it was observed that late-onset MS patients had lesser prescriptions for disease-modifying therapies compared to adult-onset MS patients. Despite treatments, including adult M2, no discernible clinical benefits were noted in slowing the progression of disabilities in late-onset MS patients. The findings highlight disparities in treatment frequency and outcomes between late-onset MS and adult-onset MS patients.
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Study on Late-Onset Multiple Sclerosis and its Clinical Characteristics
Dr. Justin Abbatemarco and Dr. Ellen Iacobaeus discuss patient characteristics, disease-modifying therapy, and disability progression in patients with late-onset MS and adult-onset MS.