Neurology Minute
Clinical Characteristics and Long-Term Outcomes of Late-Onset MS
Apr 26, 2024
Dr. Abbatemarco and Dr. Iacobaeus discuss the impact of late-onset MS, including poor prognosis risk factors, diagnostic delays, higher disability levels, less frequent treatment, and faster disease progression in patients with late-onset MS.
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Quick takeaways
- Late-onset MS patients have poorer prognosis due to risk factors, with higher disability levels at onset.
- Late-onset MS patients receive fewer disease-modifying therapies and show faster disability progression despite treatments.
Deep dives
Late-onset MS Patients Face Poor Prognosis
Late-onset MS patients, whose symptoms appear after the age of 50, were found to be associated with several risk factors linked to a poorer prognosis. A significant portion of these patients exhibited primary progressive MS. The diagnosis for late-onset MS patients experienced delays compared to those with adult-onset MS. Additionally, late-onset MS patients showed higher disability levels at onset and had a faster progression of disabilities post-onset, despite potential treatments.
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