81: Is It Your Thyroid or Are You Going Crazy? – With Dr. Izabella Wentz

In this solo episode of Thyroid Pharmacist Healing Conversations, Dr. Izabella Wentz explores the often-overlooked connection between thyroid dysfunction and mental health. Drawing from both clinical experience and her own personal journey with Hashimoto’s, Dr. Wentz explains how symptoms like anxiety, depression, panic attacks, OCD, and mood instability can be rooted in thyroid autoimmunity – even when standard thyroid labs appear “normal.”

Listeners will learn why relying solely on TSH testing can miss critical clues, how thyroid antibodies can directly affect brain function, and why nutrient deficiencies, poor T4-to-T3 conversion, and blood sugar instability can all contribute to emotional distress. This episode offers a compassionate, root-cause-focused perspective for anyone who has felt dismissed or misdiagnosed on their healing journey.

What you’ll learn in this episode:

• Why mental health symptoms are often misdiagnosed when thyroid labs look “normal.” Many doctors rely solely on TSH testing, which can remain in range for years even while autoimmune thyroid antibodies are actively attacking the thyroid and affecting brain chemistry, mood, and cognition.

• How Hashimoto’s antibodies can directly impact the brain. Elevated thyroid antibodies have been linked to anxiety, depression, OCD, panic attacks, and even more severe conditions like Hashimoto’s encephalopathy, where immune activity interferes with neurological function.

• The thyroid–mood rollercoaster many patients experience. Early-stage Hashimoto’s can cause alternating hyperthyroid and hypothyroid symptoms, leading to cycles of anxiety followed by depression, fatigue, and emotional instability that can feel confusing and frightening.

• Why T3 is critical for mental health – not just T4. Even when taking thyroid medication, poor conversion of T4 to active T3 can leave the brain under-fueled, contributing to persistent depression, brain fog, and lack of motivation.

• The overlooked nutrient deficiencies that can mimic or worsen mental health conditions. Low ferritin (iron storage), vitamin D deficiency, methylation issues (like MTHFR), selenium deficiency, and blood sugar instability can all profoundly affect mood and should be evaluated alongside thyroid health.

  
  

Tune in to learn how supporting your thyroid can transform not only your physical health, but your emotional well-being, too.

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For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: https://thyroidpharmacist.com/articles/podcast/

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