On this episode of 49ers Talk, Matt Maiocco and Laura Britt discuss who will be behind center against the Dolphins, the 49ers' wrath of injuries and how COVID-19 is affecting the NFL. Plus, former 49ers linebacker and NBC Sports Bay Area analyst Takeo Spikes joins the show to explain the 49ers’ need to improve the offensive line and what it will take to get the offense back on track.

(3:26) Who will play quarterback against the Dolphins?

(6:40) Expectations for wide receivers going forward

(10:15) Can 49ers overcome wrath of injuries?

(14:45) Spikes explains why the 49ers can slow Miami’s offense

(20:58) Spikes on how the 49ers offense can get back on track

(24:25) Spikes discusses the need for improvement on the offensive line

(31:58) Is Aiyuk a star in the making?

(34:50) NFL sees influx in COVID-19 cases

(41:25) 49ers relying on practice squad players

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250. Can the 49ers beat the Dolphins despite uncertainty at quarterback?