MCAT Basics (from MedSchoolCoach)

Isomers

Jul 29, 2025
Explore the fascinating world of isomers! Dive into structural isomers and their variations, like pentane's forms. Discover geometric isomers and how to navigate their naming with cis/trans and E/Z classifications. Unravel the complexities of stereoisomers, including enantiomers and diastereomers. Learn about conformational isomers through engaging examples like butane. Plus, understand how these concepts apply in real-life scenarios, especially in chemistry and biochemistry contexts, perfect for acing your exams!
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INSIGHT

Structural Isomers Change Properties

  • Structural (constitutional) isomers share a molecular formula but differ in atomic connectivity.
  • Different connectivities produce distinct physical properties like boiling point and density.
ADVICE

Sketch To Count Structural Isomers

  • Don't memorize formulas for counting structural isomers; sketch each possibility when needed.
  • Use structural differences to predict physical properties like boiling point and density.
INSIGHT

Geometric Isomers Are Spatial Arrangements

  • Geometric isomers differ by group arrangement around double bonds, rings, or rigid structures.
  • Cis means same side, trans means opposite side, determined by group priorities.
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