The Intern At Work: Internal Medicine 51. Transfusion without Confusion – a Practical Guide to Transfusion Medicine (Part 1)
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Mar 29, 2020 Dr. Grace Zhang, Dr. Graeme Quest, Dr. Siddhartha Srivastava, and Lucy Lan discuss blood transfusions including indications, blood types, platelet transfusions, and comprehensive guides for managing coagulopathies and trauma cases. They explore the historical origins and modern advancements in transfusion medicine, emphasizing the importance of judicious use and maintaining a balanced ratio of blood components.
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Early Blood Transfusion Example
- In 1667, Dr. Jean Baptiste Denis transfused sheep blood into a boy, often publicly.
- Most patients died, showing early transfusion was very dangerous before modern advances.
Modern Blood Transfusion Advances
- Modern transfusion separates whole blood into components with unique purposes.
- This allows safe storage and use tailored to patient needs.
Roles of Blood Components
- Blood components serve distinct roles: red cells carry oxygen, platelets initiate clotting, and plasma holds clotting factors and albumin.
- Albumin regulates fluid balance between circulations.