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Science, Spoken

Unruly Gut Fungi Can Make Your Covid Worse

Apr 22, 2024
The podcast explores how gut fungi can worsen Covid symptoms by triggering an overactive immune response. Researchers discuss the impact of severe Covid on internal fungi, leading to long-term immune changes. They also delve into personalized medicine for Covid patients with fungal overgrowth, highlighting the complexity of immune system responses post-infection.
07:37

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Quick takeaways

  • Imbalance in gut fungi during severe COVID can trigger immune overdrive, leading to respiratory complications.
  • Stem cells in severe COVID patients show primed response to fungi, potentially impacting future immune reactions.

Deep dives

The Impact of Fungi on Severe COVID Patients

During severe COVID infections, an imbalance in gut fungi can trigger an immune response that extends beyond the initial infection, leading to respiratory symptoms. Research showed that severe COVID patients had elevated levels of specific gut fungi in their microbiome, which influenced the body's immune cells like neutrophils. Antifungal treatment reduced the elevated levels of fungal-induced neutrophils, indicating a potential link between fungal overgrowth and immune system complications in COVID patients.

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