NB Hot Topics Podcast S7 E1: Best BP Meds; Preventing End-Stage CKD; ADHD & Risky Behaviours
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Sep 5, 2025 In this engaging discussion, Simon Curtis, founder of NB Medical Education, dives into cutting-edge medical research. He explores the efficacy of antihypertensive medications and the advantages of combination therapies. The talk shifts to chronic kidney disease treatments, specifically the benefits of finerenone and empagliflozin. Curtis also sheds light on ADHD medications and how they can prevent risky behaviors, emphasizing the importance of critical evaluation of current studies. It's a blend of humor, health, and insightful medical advancements!
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Embarrassing Center Parcs Moment
- Neal Tucker recounts ripping the back of his swimming shorts at Center Parcs and being told "I can see your butt" by his nephew.
- He jokes about avoiding future visits until the "ban wears off" and the story lightens the episode intro.
CKD Became A Hot Topic
- Simon Curtis notes CKD moved from a boring to a rapidly evolving field mainly due to SGLT2s and MRAs.
- He highlights implementation challenges in primary care for elderly, frail, multimorbid patients.
Why Dose Increases Often Fail
- The Lancet meta-analysis shows most BP reduction occurs at standard doses with little gain from dose doubling.
- Combination therapy at standard doses reduces systolic BP far more than increasing single-agent doses.