BMJ Best Practice Podcast

Cluster headache: an update on diagnosis and management

10 snips
Mar 13, 2023
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INSIGHT

Unique Clinical Profile And Periodicity

  • Cluster headache attacks are extremely severe, strictly one-sided, and last 15–180 minutes with multiple attacks per day.
  • They commonly occur in cycles (about eight weeks) with circadian and seasonal periodicity.
ADVICE

Diagnose By Key Clinical Questions

  • Diagnose cluster headache clinically by asking about attack duration (<4 hours), side-locked pain, autonomic signs, and restlessness.
  • Look for attacks around the eye/first trigeminal distribution and for nocturnal timing a few hours after sleep onset.
INSIGHT

Risk Links To Smoking And Sleep Apnea

  • Cluster headache shows male predominance (≈2–3:1) and strong associations with smoking and sleep apnea.
  • Passive smoke exposure and high comorbidity with sleep-disordered breathing can support the diagnosis.
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