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Freely Filtered, a NephJC Podcast
Freely Filtered 065: BEST Fluids
Feb 10, 2024
Podcast covers topics like the impact of balanced crystalloids vs saline in kidney transplants, outcomes of fluid resuscitation trials, autoimmune protocol diet, and Michael Collins (the astronaut). Also, discussions on BEST Fluids, delayed graft function, and Hawthorne Effect.
01:10:36
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Quick takeaways
- Balanced crystalloids led to decreased rates of delayed graft function and increased urine output in kidney transplant recipients.
- Postoperative fluid management practices focused on matching fluid inputs to urine output, regardless of the intervention.
Deep dives
Trial Background and Patient Characteristics
The trial focused on comparing balanced crystalloid solutions with normal saline for kidney transplant patients. The patient population was predominantly healthy with a low percentage having type 2 diabetes. In the balanced crystalloid group, patients received a higher mean volume of trial fluid than the saline group, likely due to postoperative clinical practice.
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