Febrile

40: Febrile Digest - Toxo + Transplant

6 snips
May 2, 2022
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ADVICE

Improve Transplant ID Training

  • Infectious disease trainees in transplant ID should engage in the AST education workgroup survey to improve training curriculum.
  • This effort aims to identify gaps and update transplant infectious disease education for future specialists.
INSIGHT

Toxo Risk in Transplant Mismatch

  • Toxoplasmosis risk is highest in donor-positive, recipient-negative (D+/R-) mismatches, especially heart transplant recipients.
  • Reactivation can also occur later during intensified immunosuppression for rejection without prophylaxis.
ADVICE

Toxo Prophylaxis and Prevention

  • Use trimethoprim-sulfamethoxazole regimens for toxoplasmosis prophylaxis during high immunosuppression.
  • Counsel patients to avoid raw meats, untreated water, and contact with cat litter or soil without precautions.
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