Psychedelic Medicine Podcast with Dr. Lynn Marie Morski

Encore episode: DMT Scientific Research with Dr. Chris Timmerman

Nov 25, 2020

Dr. Chris Timmerman, researcher at Imperial College, discusses the neurology of DMT, including how brainwaves change and the pattern of cortical activation. He explores the similarities between DMT experiences and near-death experiences, and the difficulties of studying the phenomena. Dr. Timmerman also shares his research on the impact of music in psychedelic therapy.

01:00:19

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Episode guests

Chris Timmerman

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Quick takeaways

DMT's ability to induce immersive experiences similar to near-death experiences and the potential therapeutic applications of DMT.

The role of music in shaping the emotional and therapeutic outcome of psychedelic experiences and its positive impact on the overall psychedelic therapy process.

The need for ethical navigation and grounding of profound insights and revelations from psychedelic experiences through psychedelic apprenticeship and maintaining a delicate touch in guiding individuals' experiences.

Deep dives

Research on DMT and its Potential for Mental Health Interventions

Researcher Dr. Chris Timmerman conducts neuroimaging studies on DMT and its effects on mental health interventions. DMT's ability to induce immersive experiences similar to near-death experiences is explored. The brain patterns observed during DMT experiences, such as increased delta and theta waves, are compared to dreaming states. The role of the serotonin system and serotonin-2A receptor in DMT's effects on the brain is explained. The potential therapeutic applications of DMT and its impact on neurogenesis are also discussed.

Introduction

2min

DMT Scientific Research and its Potential for Mental Health Interventions

2min

Exploring the Physiology of DMT

11min

Effects of IV DMT on the Brain

7min

Theta Waves, Immersion, and Predictive Coding in Neuroscience

3min

Exploring Top-Down and Bottom-Up Information Flow in the Brain and the Effects of DMT

4min

DMT and Near-Death Experiences

17min

The role of music in psychedelic therapy

15min

Chris Timmermann, PhD, is a researcher at Imperial College, where he conducted the first neuroimaging studies of DMT in healthy volunteers and its potential for mental health interventions. He is also conducting research concerning the effects that psychedelics have on belief systems and the ethical implications associated with the mainstreaming of these substances.

In this episode, Chris Timmerman discusses what happens neurologically when DMT is administered. He talks about his research into neuroimaging and how the brainwaves change during DMT experiences, and how those changes can help elucidate some of the mechanisms of psychedelic states. He also breaks down the concept of cortical activation and how DMT experiences lead to a pattern of cortical activation that mimics that of visual stimulation.

Dr. Timmerman also discusses how DMT experiences are often compared to what happens to the body when it has a near-death experience. He explains some of the difficulties of studying these effects and how to ethically study the phenomenon of near-death experiences. In addition to his work on DMT, Dr. Timmerman also shares some of his research on the impact of music in psychedelic therapy, and how it can help comfort people facing trauma.

In this episode:

How DMT interacts with our physiology
Current scientific research on DMT
The correlation between DMT and near-death experiences
How alpha, delta and theta brain waves are affected by DMT
Why people think DMT use can lead to tolerance
The role of music in psychedelic therapy
What psychedelic apprenticeships are and how they can help with healing

Quotes:

"DMT is incredibly unique because it is able to generate simulations of sorts. The level of immersion is radical, complete. People with their eyes closed, they feel kind of detached from their environment, but they are experiencing a world of experience." [5:52]

"We developed a map of this DMT story for each participant. We found three main components: one there was a visual component in the experience, we found a bodily component [a somatic effect], and an emotional effect. And we found that these different parts of the DMT story - the visual, the bodily, and the emotional - had different brain signatures." [18:55]

"There have been some animal studies, or very promising ones, in which not only DMT but also LSD and ketamine has been shown to have important properties associated with neurogenesis." [35:09]

"The use of psychedelics by western populations is fairly new. We don't have that know-how or that expertise like some indigenous cultures, has for generations." [46:49]

Links:

Get 20% off everything at Octagon Biolabs (octagonbiolabs.com) with coupon code 'plantmedicine'

Follow Dr. Timmerman on Twitter

Follow Dr. Timmerman (and check out his music) on InstagramFollow Chris on Instagram and listen to his music

Center for Psychedelic Research at Imperial College

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