Healthy Living Healthy Living - January 11th
Jan 11, 2026
Guest
Ben McDonald
Guest
Tanvir Ahmed
Guest
Jeremy Barr
Guest
Nick Huntington
Guest
Casey Beros
Guest
Mark Polizzotto
Guest
Clay Gollage
Guest
Stephen Robertson
Guest
Steve Nichols
Guest
Ben Herbert
Dr. Ben Herbert, a researcher specializing in xenotransplantation, discusses the potential of pig organs for human transplants and the ethical concerns involved. Professor Steve Nichols explains CRISPR gene editing’s impact on lipid disorders, detailing human trials targeting ANGPTL3. Professor Stephen Robertson contrasts A1 and A2 milk, revealing A2's benefits for cognition in the elderly. Dr. Clay Gollage links shingles vaccination to reduced dementia risk, while Mark Polizzotto explores new RNA polymerase therapies for cancer. Casey Beros shares caregiver strategies amidst the 'sandwich generation' challenge.
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Episode notes
Xenotransplantation Advances And Limits
- Gene-edited pig organs have overcome hyperacute rejection but face slower immune rejection over months.
- Dr Ben Herbert predicts months-to-year survival and sees xenotransplantation teaching immunology rather than becoming the ultimate solution.
Discuss Permanence Before CRISPR Lipid Therapy
- Consider one-off CRISPR therapies for hard-to-treat lipid disorders when other drugs fail.
- Discuss risks and permanence with clinicians since the liver edit is lifelong and early trials are small.
A2 Milk May Benefit Gut And Cognition
- A2 milk lacks the BCM7 peptide released from A1 beta-casein and may reduce gut inflammation and opioid-like effects.
- The A2 milk trial found bigger cognitive, sleep and vitamin D gains in elderly people with mild cognitive impairment.
