Big Think

Meet the scientist that made a machine to measure life itself | Lee Cronin

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Jun 2, 2025
Lee Cronin, a pioneering chemist behind Assembly Theory, challenges conventional definitions of life. He proposes that life is all about producing complexity at scale rather than just biological makeup. Cronin discusses his groundbreaking Assembly Index, which quantifies the complexity of objects, suggesting the universe has a ‘choosy’ nature. He also reveals his team's ambitious project to build a machine that can identify lifelike behaviors in random chemistry, potentially unlocking secrets of life's origins and even allowing us to create life in a lab.
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INSIGHT

Life as Scaled Complexity

  • Lee Cronin defines life as any system that can produce complexity at scale through non-random processes.
  • He introduces Assembly Theory to measure how much selection shaped the complexity of objects and systems.
INSIGHT

Quantifying Life with Assembly Theory

  • Assembly Theory quantifies life by calculating the assembly index times the number of identical objects.
  • This approach measures how much selection has gone into creating complex systems, revealing life as a universal phenomenon.
ADVICE

Building Life via Selection Engines

  • Use random chemistry and selection engines to search for molecules exhibiting life-like timescale features.
  • Focus on objects that persist, replicate, and resist decay to identify emergent life.
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