The Naked Scientists Podcast

Proteomics promises a revolution in preventative medicine

Oct 28, 2025
Join Andrew Frankel, a seasoned nephrologist, and Richard Lipscomb from Proteomics International, as they explore the groundbreaking potential of proteomics in predicting future diseases. Kirsten Peters reveals how blood protein biomarkers can anticipate conditions like kidney disease, esophageal cancer, and endometriosis years ahead of traditional methods. Smita Sinna discusses patient engagement and the economics of early testing. Together, they highlight a paradigm shift in healthcare from reactive treatment to proactive prevention, emphasizing the transformative possibilities of molecular science.
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INSIGHT

Kidney Disease Detected Too Late

  • Chronic kidney disease is often detected far too late using standard tests.
  • Early identification would let new drugs and lifestyle changes prevent dialysis and transplants.
ANECDOTE

Nephrologist Shifted From Treatment To Prevention

  • Andrew Frankel has spent 35 years caring for people with end-stage kidney failure.
  • Over the last decade he shifted focus to preventing progression rather than treating failure.
INSIGHT

Proteins Reveal Ongoing Disease Processes

  • Proteomics measures protein-level changes that reflect current processes and environment.
  • Protein panels reveal disease-specific fingerprints that genetics alone cannot capture.
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