

June 2025: Placenta Accreta Spectrum- Part 1
May 15, 2025
In this episode, guest Lisa Zuckerweiss, an Associate Professor of Obstetrics and Gynecology and Director of Maternal-Fetal Medicine at the University of Virginia, discusses the complexities of Placenta Accreta Spectrum (PAS). She emphasizes the increasing incidence linked to cesarean deliveries and the urgent need for better screening and management strategies. The conversation includes insights from a NICHD workshop aimed at enhancing collaboration among experts, sharing patient experiences, and advocating for a patient-centered approach in treatment.
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PAS Rising with Cesarean Rates
- Placenta Accreta Spectrum (PAS) is increasing due to high cesarean delivery rates.
- This condition causes significant maternal and neonatal morbidity and mortality.
PAS Incidence and Risk Factors
- PAS incidence estimates vary widely from 0.01% to 1%, making it hard to define true prevalence.
- The main risk factor is prior cesarean delivery, making PAS largely an iatrogenic disease.
Critical Need for Early Diagnosis
- Up to 70% of accreta cases aren't diagnosed before delivery, causing missed opportunities for specialized care.
- Improving diagnostics and risk stratification in community settings is urgently needed.