Digital Health Heavyweights Episode 34: Trupti Mukker, Co-Founder and COO of Complement 1
In this episode, Norm Volsky sits down with Trupti Mukker, Co-Founder and COO of Complement 1, the digital cancer rehabilitation platform, 1st non-pharma treatment layer helping patients complete treatment, recover faster, and lower costs. Trupti shares her journey into healthcare, the inspiration behind Complement 1, and how digital cancer rehabilitation, rooted in exercise, nutrition, and stress management can significantly improve outcomes for patients during and after treatment. The conversation explores the clinical rigor behind Complement 1’s evidence-based approach, how the platform achieves 90% engagement and cost savings for payers and health systems, and the growing role of AI in personalizing rehabilitation for every cancer type, recovery stage, and side effects. Trupti also highlights the importance of daily clinical support in improving treatment adherence, quality of life, and long-term survivorship outcomes.
Key Takeaways:
👩⚕️ Trupti Mukker transitioned to healthcare to make a meaningful impact.
💪 Complement 1 delivers digital cancer rehabilitation—a daily non-pharma treatment layer integrated into oncology care.
📉 Less than 5% of cancer patients adhere to lifestyle modifications that can drastically improve outcomes.
🏃♀️ Exercise and structured rehabilitation reduce fatigue and increase energy levels during treatment.
🤝 Daily, human-led support drives real adherence and measurable outcomes.
📊 Evidence shows lifestyle therapy can cut recurrence risk by up to 35–40%.
✅ Complement 1’s program is 100% evidence-based and backed by clinical evidence.
💰 The platform achieves 90%+ engagement and cost savings for health systems and payers.
🧬 Personalized rehabilitation is essential across cancer types and recovery stages.
🔮 The future of oncology includes digital cancer rehabilitation as a standard, AI-powered layer of care.
Chapters
00:00 Introduction to Complement 1 and Its Mission
02:07 Trupti's Journey into Healthcare
04:30 The Importance of Lifestyle Interventions in Cancer Care
07:51 Personalized Patient Experience with Complement One
11:37 The Impact of Lifestyle Changes on Cancer Recurrence
14:22 Maintaining Clinical Rigor in a Human-Centric Model
17:08 Driving Engagement and Cost Savings
19:30 Partnerships and Market Response
21:30 Personalization in Cancer Care
24:19 Patient Success Stories
26:18 The Future of Lifestyle Medicine and AI
28:05 Advice for Founders in Healthcare
29:01 Trupti's Personal Health Practices
34:07 Outro
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