There's new evidence that intermittent fasting boosts immunity, improves cognition function, helps with weight loss, and even reverses certain diseases. How is it possible that simply restricting meal times can alter how your body functions? There are several ways to approach fasting including, intermittent fasting, alternate-day fasting, and water fasting. Yet, many people who begin a fasting regimen struggle to maintain a routine long enough to reap the benefits. So how do you choose a sustainable and healthy approach? In this episode, Dr. Weil and Dr. Maizes welcome Dr. Valter Logo, director of the Longevity Institute at the University of Southern California, the director of the Longevity and Cancer Program at the Institute of Molecular Oncology in Milan, Italy, and author of the book "The Longevity Diet". Dr. Longo explains fasting's effects on the immune system and the microbiome, discusses the various approaches, and advocates for FMD or "fasting-mimicking diet".