Freely Filtered, a NephJC Podcast FF 82 DDAVP up the nose to prevent biopsy bleeding
Aug 8, 2025
Vandana Niyyar, Professor of Medicine at Emory School of Medicine and a leader in interventional nephrology, discusses groundbreaking approaches in kidney biopsy procedures. She highlights the advantages of using Desmopressin (DDAVP) to reduce bleeding, revealing its effectiveness in patient care. The conversation also covers outpatient biopsy protocols, innovations in vascular access, and evolving practices based on recent studies. Niyyar emphasizes the importance of individualized care and the impact of training on patient outcomes in nephrology.
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Unit Confusion Around Platelet Counts
- Joel Topf misreads platelet units in a humorous exchange that exposes study-unit confusion.
- The moment highlights how unit differences across regions can complicate trial interpretation.
Wide Variation In DDAVP Practice
- Joel Topf and colleagues report wide variation in DDAVP use across centers and operators.
- Practices range from routine pre-biopsy dosing to rare, individualized administration.
Observe Early After Kidney Biopsy
- Vandana Niyyar advises early post-biopsy monitoring because complications usually appear soon.
- Consider first-case scheduling and several hours of observation before same-day discharge.