Eagle's Eye View: Your Weekly CV Update From ACC.org Lp(a) and CV Risk; CRP Levels and High-Risk Vulnerable Plaque post-NSTEMI; Pulsed Field Ablation vs. Cryoablation for Paroxysmal AFib
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Apr 30, 2025 Delve into the intriguing relationship between Lp(a) levels and cardiovascular risk. Uncover how high-sensitivity C-reactive protein can identify high-risk plaques after NSTEMI. Explore the battle between pulsed field ablation and cryoablation in treating paroxysmal AFib. Each topic reveals cutting-edge insights in cardiovascular health, backed by extensive research and clinical trials.
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Lp(a) Links to Cardiovascular Risk
- Higher Lp(a) levels strongly correlate with increased subclinical atherosclerosis and cardiovascular risk.
- Women, older adults, and those with metabolic risk factors tend to have elevated Lp(a).
Measure Lp(a) for Emerging Therapies
- Measure Lp(a) more frequently as new targeted therapies emerge.
- Consider PCSK9 inhibitors since they can modestly reduce Lp(a) along with LDL cholesterol.
hsCRP Indicates Vulnerable Plaques
- Elevated hsCRP levels associate with more vulnerable, lipid-rich plaques in patients post non-STEMI.
- Higher hsCRP correlates with inflammation markers and increased adverse cardiovascular events.