Rheumnow Podcast
Immunosuppression Increasing (2.23.2024)
Feb 23, 2024
Exploring immunosuppression, prevalence, and its implications. Highlights include recent autoimmune disease research on inflammatory arthritis referrals, myositis diagnosis, lupus nephritis outcomes, infections in lupus patients, and advancements in treatment for autoimmune diseases like psoriasis and RA.
24:23
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Quick takeaways
- Immunosuppression can result from diseases or drugs, impacting vulnerability to diseases like cancers.
- Early rheumatology referrals are increasing, but timely initiation of demarcation therapy remains a challenge.
Deep dives
Understanding Immunosuppression
Immunosuppression is defined as a state that can be caused by disease or drugs, leading to an increased vulnerability to illnesses like cancers, immunodeficiency disorders, and more. While medications like chemotherapy and biologics can be immunosuppressive, cytokine inhibitors are often more anti-inflammatory than immunosuppressive when used alone. A recent JAMA report revealed that in the USA, the prevalence of immunosuppression is around 6.6%, influenced by both disease-related factors and medication usage.
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