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GABAergic Compounds - Are They Really Sedating?
The overall effects profile is very physically and mentally relaxing, but it's not particularly sedating. It does seem like when compared to other GABAergic compounds, linolol, both SNR linolol lack a lot of locomotor suppression. When you are looking at sedation or even stimulation in an animal model, you are basically tracking if I give this animal like a rat or a mouse,. If I give them linolol or let’s say we give them caffeine, then what do we see? Well, when you give a rat caffeine, they will start moving around a little bit more so their locomotor activity is enhanced. And the more you dig, the more you
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