The chapter explores the physical toll and injuries faced by older fighters in MMA, highlighting the challenges of aging in the sport and proposing a Legends League for older fighters. Discussions also touch on knee injuries, the use of stem cells for recovery, the importance of supportive medical staff, and the resources available at the UFC Performance Institute. Additionally, the chapter delves into the success of Pride in Japan, the decline of a prominent MMA organization, potential boxing matches for fighters, and strategic considerations in potential matchups.