Optimizing Thrombolytic Therapy in Pulmonary Embolism

The chapter delves into the dosing strategies of thrombolytic therapy for pulmonary embolism, proposing lower doses like 50 milligrams or quarter dose thrombolysis to minimize bleeding risk. It discusses different management approaches based on the severity of the condition for various groups of patients, including those with contraindications to full-dose TPA. The conversation also explores alternative treatments like catheter-directed thrombolysis and percutaneous mechanical thrombectomy, emphasizing the need for more comprehensive trials to evaluate efficacy.