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Mitochondrial Warfare: Cancer and Immune Cell Dynamics
This chapter explores the unique ability of cancer cells to transfer dysfunctional mitochondria to immune T-cells, potentially compromising the immune response against tumors. It investigates the mechanisms of mitochondrial transfer, including direct contact and extracellular vesicles, and the implications for T-cell function and tumor growth. Additionally, the chapter addresses the promising potential for this understanding to enhance immunotherapy strategies in cancer treatment.