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Self Experiments In the Biochemically Unoptimized State

Mastering Nutrition

CHAPTER

How to Randomize a Trial of Acute Phenomena

randomization and control is meant to tell me what biochemical phenomena are truly operating during this period. I would have that it would have been better to include washout periods, which are spaces of normal time between trials in order to prevent epigenetic adaptations to fasting or carb loading across trials. However, as it stood this took me months and it could have taken a year or longer if we'd done that. Even worse than with adding washout periods,. randomizing across periods of improved improved and worsened biotin status was too difficult. That would take many years. Therefore, randomization was limited to trials of acute phenomena that could be observed within hours such that sufficient repeated observations could be collected over a

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