The Problem with Most Published Research Findings

In our second episode, we discuss the role of skepticism in science, a topic that relates closely to the title of our podcast. Given that the scientific enterprise is essentially an exercise in organized skepticism, how can we maintain a healthy amount of skepticism while also ensuring that scientists don't slip into cynicism or nihilism? 

Shownotes

• Opening quote by Imre Lakatos from Science and Pseudoscience. Hear it from the man himself. 
  
  
• Ego depletion
  
  
• Ioannidis, J. P. (2005). Why most published research findings are false. PLoS Medicine, 2(8), e124. https://doi.org/10.1371/journal.pmed.0020124
  
  
• Wacholder, S., Chanock, S., Garcia-Closas, M., El Ghormli, L., & Rothman, N. (2004). Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. Journal of the National Cancer Institute, 96(6), 434-442. DOI: 10.1093/jnci/djh075

• Quote by Debra Mayo. Original reference: Mayo, D. G. (2018). Statistical inference as severe testing: How to get beyond the statistics wars. Cambridge University Press.