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Freely Filtered 057: NephMadness 2023 TMA

Freely Filtered, a NephJC Podcast

CHAPTER

What's the MAC Attack?

The whole purpose of the complement system, you know, really nature designed it for us to design to protect us from infections. But what ends up happening in disease is that the guardian of intracellular space, intra vascular, it's the guardian of the intra vascular space. So because of that feedback loop, that amplification loop, it's that pathway that needs to really be kept in check. Because if it's let go, then the activation keeps going.

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