2min chapter

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#133 – Manolis Kellis: Biology of Disease

Lex Fridman Podcast

CHAPTER

The Puzzle of How Little Perturbations Lead to Disease?

Every one of us carries six million perturbations. Six million unique genetic variants that are segregating in the human population. The reason why two twins are identical is because these variants completely determine the way that I'm going to look at exactly 93 years of age. Most of them don't do anything, but some of them lead to all of the phenotypic differences we see between us.

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