Is There a Repetition Mutation Testing in EGFR?

Oncologists hear a lot about doing that in EGFR. In EGFR you have the issue of transformation of small cell incidentally I don't know does that occur with alk and also what about repeat mutation testing liquid biopsies Ross from a practical perspective outside of research is there any reason for a doc and community based practice to do that? So it's a kind of similar argument. When people on the targeted therapy develop a quiet resistance they don't always just turn back on the same signaling pathway. We believe there's a pie child with different driver oncogenes at the startThere's a pieChild with different mechanism resistance at the time of a quiet resistance.