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Bipolar Upgrade 3: Lurasidone

The Carlat Psychiatry Podcast

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The Opposite for Bipolar Depression

The only generic antipsychotics for bipolar depression were weighed down with sedation and metabolic side effects. But this year, lorazadone finally went generic, and the price has fallen fast. Depression occupies some 40 to 60% of the lifespan in bipolar disorder. The odds that antipsychotics are going to work in depression are against them from the start.

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