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Neurotech Special: Whole Brain Emulation and Artificial General Intelligence

Foresight Institute Radio

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The Integrity of Expansion Microscopy

Robert: I'm trying to figure out how to get samples that can be imaged by x-ray um expansion microscopy and trying to do a proof of concept for x-ray expansion microscopy. He says the density is too low for the microscope to pick up any good contrast but there's been a new preprint that came out that is called unclearing microscopy which uses a horseradish perox base, he says. Robert: Can you not simply cryo protect the expanded slices and then cool them down so they're vitrified? You end up actually potentially with more damage if you cool it down according to Adrienne Wanner at WashU on a totally different project

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