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PT403 – Melanie Pincus, Ph.D & Manesh Girn – Understanding the Brain: Psychedelic Neuroscience Demystified

Psychedelics Today

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The Effects of Chronic Stress on the Brain

Chronic stress really takes a toll on the brain at various spatial levels. It's disruptive to a bunch of the neurotransmitter systems and that has profound consequences for individuals. Having high chronic stress means an upregulation of inflammatory markers, which then create brain inflammation. This also intersects with your gut microbiome, which I talk about in one of my lectures. These things are all intertwined with stress and chronic stress and then trauma. And it's all interconnected.

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