What's Different From LISPs?

In traditional LISPs, the core data structures are mutable. In closure, all of the library code is written in terms of abstractions. That means that the entire sequence library works with anything that's remotely sequential or to provide a sequential view. The second area in which closure differs is that, you know, LISPs is very old. And scheme is very old and they actually predate some modern concepts like interfaces and polymorphic API design.