Audio long read: ‘Almost magical’ — chemists can now move single atoms in and out of a molecule’s core
Nature Podcast
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The Benefits of Skeletal Editing
New kinds of chemical reaction that synthesized molecules have transformed drug discovery. If skeletal editing could be applied to a broad range of molecules, adding or removing specific atoms with complete selectivity and without damaging existing functional groups would rank alongside past innovations. But for skeletal editing to be generalizable, the techniques will have to work reliably on thousands of different molecules.
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