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Oncology Today with Dr Neil Love: Management of HER2-Altered Non-Small Cell Lung Cancer?

Lung Cancer Update

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TDXD - A New Antibody Drug Conjugate Compared to TDM1

TDXD is a new antibody drug conjugate compared to TDM1s. It's the same Trastuzumab backbone but it has a different warhead, and it's DXD in terms of DM1. The linker linking the warhead to the missile is also a slightly different linker in terms of engineering. And we have seen activity in the TDM1 resistant breast, her two positive breast cancers initially. But now certainly the Destiny breast 03 and other trials have shown that it's superior to TDM 1 even in the second line set.

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