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Freely Filtered 057: NephMadness 2023 TMA

Freely Filtered, a NephJC Podcast

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Is Avocopan an Oral C5 Inhibitor?

For factor B and C3, I am particularly excited about them for C3G because they are targeting more proximal in the complement pathway. And then the Avocopan, which we're seeing approved for Incavascularitis, it's an oral C5 inhibitor. Do folks think about that as like a future maintenance therapy that's easier than coming in for IV echolizumab? Or I know that's super off label and no one should be doing that, but right.

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