Cardiac Regenerative Capacity and Tissue Engineering

The chapter explores the potential for cardiomyocyte regeneration in neonatal hearts through metabolic changes and genetic manipulations. It also discusses the challenges and advancements in integrating stem cell-derived cardiomyocytes into the host myocardium for improved cardiac function, highlighting the importance of mature endothelial cells. Furthermore, it delves into tissue engineering applications for tracheal reconstruction, showcasing a bioengineered trachea project that demonstrated successful outcomes in rabbits.