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Suzanne Defkota, PhD is the director of microbiome research at Cedars-Cenai Medical Center in Los Angeles. Her lab studies the role of the gut microbiome in inflammatory and metabolic diseases originating in the GI tract. In this conversation, we retrace important facts about the microbiomes that make up our immune system. We also discuss whether the microbiome is associated with certain conditions or causes them,. how our microbiome could affect food allergies, intolerances, IBD, and obesity.

Episode #267. Join me for a deep dive into the influence of the gut microbiome on inflammation and metabolic disease. In this fascinating exchange with Dr Suzanne Devkota, we explore the role of the gut in these conditions, shedding light on food allergies, IBD, and obesity. You’ll learn the practical tips you need to nurture a healthy microbiome, as well as gain a better understanding of what we do – and don’t – know about this incredible system.

Specifically, we discuss:

Intro (00:00)
The evolving field of microbiome research (02:13)
Gut microbe on social media (09:32)
Microbiome definition (12:48)
Why the focus on gut bacteria? (13:55)
Differences in Microbes (16:02)
Microbial shifts and adaptations (18:45)
Microbes perturbations (21:35)
Human microbiome in evolution (23:54)
Healthy microbiome and diversity (27:47)
Is the microbiome the sole driver of metabolic diseases? (33:05)
Dietary patterns and FODMAP intolerance (41:07)
Saturated fat and gut health (49:15)
Microbiome metabolites and heart disease risk (57:42)
Inflammatory bowel disease (IBD) and dysbiosis (1:02:09)
Food additives (1:12:29)
Supporting the microbiome in IBD (1:15:29)
Microbiome's interaction with fat cells (1:16:52)
Short-chain fatty acids and appetite regulation (1:29:26)
Practical tips for nourishing a healthy gut (1:31:05)
Microbiome's interaction with Polyphenols (1:38:43)
On supplements and fermented foods (1:39:15)
Factors affecting gut health beyond nutrition (1:46:22)
Outro (1:50:10)

Connect with Dr Suzanne Devkota on Instagram and Twitter. Learn more about her research at http://www.devkotalab.com/thelab.

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Enjoy, friends.

Simon

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Simon Hill, MSc, BSc (Hons)

Creator of theproof.com and host of The Proof with Simon Hill

Author of The Proof is in the Plants

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